NUSAP1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5111726-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA5111726 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
NUSAP1
Classification
Polyclonal
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q9BXS6
Gene Symbols
NUSAP1
Immunogen
Recombinant Protein corresonding to Human NUSAP1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry
Conjugate
Unconjugated
Gene
NUSAP1
Gene Alias
2610201A12Rik; AI481307; ankt; AW547774; BB165529; BM037; BM-037; fb76a01; fi37a11; hypothetical protein; LNP; nucleolar and spindle associated protein 1; nucleolar and spindle-associated protein 1; nucleolar protein ANKT; NuSAP; NUSAP1; PRO0310; PRO0310p1; Q0310; SAPL; sb:cb490; Unknown (protein for IMAGE:7053642); Unknown (protein for MGC:134490); wu:fb76a01; wu:fi37a11; YF-9
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
51203
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Immunogen sequence: THKLKTITGN SAAVITPFKL TTEATQTPVS NKKPVFDLKA SLSRPLNYEP HKGKLKPWGQ SKENNYLNQH VNRINFYKKT YKQPHLQ Ubiquitin: exists either covalently attached to another protein, or free (unanchored)
- When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains)
- Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B
- Linear polymer chains formed via attachment by the initiator Met lead to cell signaling
- Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed
- When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling
- 60S ribosomal protein L40: component of the 60S subunit of the ribosome
- Ribosomal protein L40 is essential for translation of a subset of cellular transcripts, and especially for cap-dependent translation of vesicular stomatitis virus mRNAs.