PIPA5112046
Lassa virus RING finger protein Z Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5112046-Each-of-1 | In Stock | ₹ 43,476.50 |
PIPA5112046 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,476.50
GST (18%): ₹ 7,825.77
Total Price: ₹ 51,302.27
Antigen
Lassa virus RING finger protein Z
Classification
Polyclonal
Conjugate
Unconjugated
Gene Alias
Lassa virus
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of Lassa virus RING finger protein Z. The exact sequence is proprietary.
Quantity
100 μL
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Concentration
1.11 mg/mL
Formulation
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Target Species
Virus
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Plays a crucial role in virion assembly and budding
- Expressed late in the virus life cycle, it acts as an inhibitor of viral transcription and RNA synthesis by interacting with the viral polymerase L
- Presumably recruits the NP encapsidated genome to cellular membranes at budding sites via direct interaction with NP
- Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins involved in vesicle formation pathway
- The budding of the virus progeny occurs after association of protein Z with the viral glycoprotein complex SSP-GP1-GP2 at the cell periphery, step that requires myristoylation of protein Z
- Also selectively represses protein production by associating with host eIF4E.