PIPA5112059

CCR2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5112059-Each-of-1 In Stock ₹ 43,476.50

PIPA5112059 - Each of 1

₹ 43,476.50

In Stock

Quantity

1

Base Price: ₹ 43,476.50

GST (18%): ₹ 7,825.77

Total Price: ₹ 51,302.27

Antigen

CCR2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Ccr2

Gene Alias

C-C chemokine receptor type 2; C-C CHEMOKINE RECEPTOR TYPE 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2) (JE/FIC RECEPTOR) (MCP-1 RECEPTOR); C-C CKR-2; C-C motif chemokine receptor 2; Cc-ckr2; CC-CKR-2; Ccr2; CCR-2; Ccr2a; CCR2B; CD192; CD192 antigen; chemoattractant protein-1 receptor; chemokine (C-C motif) receptor 2; chemokine (C-C) receptor 2; chemokine receptor CCR2; Ckr2; Ckr2a; Ckr2b; CMKBR2; hCG_14621; JE/FIC receptor; Mcp1 receptor; MCP-1 receptor; Mcp1r; MCP-1-R; MIP-1 alphaR; mJe-r; Monocyte chemoattractant protein 1 receptor; monocyte chemotactic protein 1 receptor

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

729230

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunoprecipitation, Western Blot

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

P41597

Gene Symbols

Ccr2

Immunogen

A synthetic peptide corresponding to the N-terminus of the Human CCR2/cd192

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • CCR2, a chemokine receptor, is a regulator of monocyte/macrophage traffickings and is upregulated in response to inflammation
  • Resistance to HIV-1 infection or delayed progression to AIDS may be linked to CCR2 polymorphisms
  • The ligand for CCR2 is monocyte chemoattractant protein (MCP-1), a chemokine produced by endothelial cells, smooth muscle cells, and macrophages
  • Activation of monocytes by MCP-1 may mediate the monocytic infiltration of tissues in atherosclerosis and other inflammatory disorders including rheumatoid arthritis, alveolitis, and tumor infiltration
  • Two isoforms are produced by alternative splicing
  • CCR2 has been reported to be expressed in a wide variety of tissues, including blood, brain, heart, kidney, liver, lung, ovary, pancreas, spinal cord, spleen, thymus, and vessel
  • Increased expression of CCR2 has been documented in CD3+ lymphocytes in rheumatoid arthritis
  • ESTs have been isolated from liver/spleen and prostate libraries.