PIPA5112135

SETD8 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5112135-Each-of-1 In Stock ₹ 42,497.50

PIPA5112135 - Each of 1

₹ 42,497.50

In Stock

Quantity

1

Base Price: ₹ 42,497.50

GST (18%): ₹ 7,649.55

Total Price: ₹ 50,147.05

Antigen

SETD8

Classification

Polyclonal

Conjugate

Unconjugated

Gene

KMT5A

Gene Alias

2410195B05Rik; AA617402; AW536475; H4-K20-HMTase; H4-K20-HMTase KMT5A; H4-K20-HMTase SETD8; H4-K20-specific histone methyltransferase; H4K20-specific histone methyltransferase splice variant Set8b; histone methyltransferase Pr-set7/Set8; histone-lysine N-methyltransferase KMT5A; histone-lysine N-methyltransferase SETD8; KMT5A; lysine (K)-specific methyltransferase 5A; lysine methyltransferase 5A; lysine N-methyltransferase 5A; Lysine-specific methylase 5A; N-lysine methyltransferase KMT5A; N-lysine methyltransferase SETD8; PR/SET domain containing protein 8; PR/SET domain-containing protein 07; PR/SET07; PRSET7; PR-Set7; RGD1305893; SET domain containing (lysine methyltransferase) 8; SET domain containing protein 8 variant 1; SET domain containing protein 8 variant 2; SET domain-containing 8; SET domain-containing protein 8; SET07; SET8; SETD8; Unknown (protein for MGC:134426)

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

387893

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Immunoprecipitation, Western Blot

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

Q9NQR1

Gene Symbols

KMT5A

Immunogen

Recombinant Human PR-Set7/KMT5A Protein

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • This product can be used in direct ELISA
  • SETD8 is a histone methyltransferase that specifically monomethylates 'Lys-20' of histone H4
  • H4 'Lys-20' monomethylation is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression
  • The protein mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes
  • It is required for cell proliferation, probably by contributing to the maintenance of proper higher order structure of DNA during mitosis
  • It is also involved in chromosome condensation and proper cytokinesis
  • Nucleosomes are preferred as substrate compared to free histones.