eIF3e Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5112192-Each-of-1 | In Stock | ₹ 42,497.50 |
PIPA5112192 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,497.50
GST (18%): ₹ 7,649.55
Total Price: ₹ 50,147.05
Antigen
eIF3e
Classification
Polyclonal
Conjugate
Unconjugated
Gene
EIF3E
Gene Alias
48kDa; eIF-3 p48; eIF3e; eIF3-p46; EIF3-P48; EIF3S6; eukaryotic translation initiation factor 3 subunit 6; Eukaryotic translation initiation factor 3 subunit E; eukaryotic translation initiation factor 3 subunit E isoform 2 transcript; eukaryotic translation initiation factor 3 subunit E-like protein; eukaryotic translation initiation factor 3, subunit 6 (48kD); eukaryotic translation initiation factor 3, subunit 6 48kDa; eukaryotic translation initiation factor 3, subunit E; eukaryotic translation initiation factor subunit E-like protein; Int6; mammary tumor integration site 6; mammary tumor-associated protein INT6; mammary tumor-associated protein INT-6; MMTV integration site 6; murine mammary tumor integration site 6 (oncogene homolog); NEWGENE_1311521; Viral integration site protein INT-6; viral integration site protein INT-6 homolog
Host Species
Rabbit
Purification Method
Antigen affinity chromatography, Protein A
Regulatory Status
RUO
Gene ID (Entrez)
3646
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.03% ProClin 300; pH 7
Gene Accession No.
P60228
Gene Symbols
EIF3E
Immunogen
E. coli-derived Human EIF3E fragment
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis
- The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC)
- The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition
- The eIF-3 complex is also required for disassembly and recycling of post termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation
- Required for nonsense-mediated mRNA decay (NMD); may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway
- May interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins.