PIPA5112255
MAP1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5112255-Each-of-1 | In Stock | ₹ 43,120.50 |
PIPA5112255 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,120.50
GST (18%): ₹ 7,761.69
Total Price: ₹ 50,882.19
Antigen
MAP1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MOAP1
Gene Alias
AA987038; MAP1; Map-1; Moap1; Modulator of apoptosis 1; paraneoplastic antigen like 4; paraneoplastic antigen Ma4; paraneoplastic Ma antigen family member 4; PNMA4
Host Species
Rabbit
Purification Method
Antigen affinity chromatography, Protein A
Regulatory Status
RUO
Gene ID (Entrez)
64112
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.03% ProClin 300; pH 7
Gene Accession No.
Q96BY2
Gene Symbols
MOAP1
Immunogen
E. coli-derived Human MAP1/MOAP1 fragment
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells
- Disruption of this process has been implicated in a variety of diseases such as cancer
- Members of the Bcl-2 family are known to be critical regulators of this process
- These proteins are characterized by the presence of several conserved motifs termed Bcl-2 homology (BH) domains
- A related protein termed MAP-1 has recently been identified
- This protein contains a BH3-like domain and induces caspase-dependent apoptosis in mammalian cells when overexpressed
- It forms homodimers and associates with Bcl-2 family members such as Bax, Bcl-2, and Bcl-XL in vitro and in vivo
- It has been suggested that MAP-1 associates with the tumor suppressor RASSF1A following death receptor activation, allowing a conformational change in Bax that leads to cellular apoptosis.