PIPA5112645

PEAR1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5112645-Each-of-1 In Stock ₹ 43,476.50

PIPA5112645 - Each of 1

₹ 43,476.50

In Stock

Quantity

1

Base Price: ₹ 43,476.50

GST (18%): ₹ 7,825.77

Total Price: ₹ 51,302.27

Antigen

PEAR1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PEAR1

Gene Alias

3110045G13Rik; hPEAR1; Jagged and Delta protein; Jedi; Jedi-1; MEGF12; mPEAR1; Multiple EGF-like domains protein 12; multiple EGF-like-domains 12; multiple epidermal growth factor-like domains protein 12; Pear1; Platelet endothelial aggregation receptor 1; protein Jedi; RGD1305653; RP11-107D16.3

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

295293, 375033, 73182

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

Applications

ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

3.24 mg/mL

Formulation

PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.

Q5VY43, Q8VIK5

Gene Symbols

PEAR1

Immunogen

Recombinant Human Platelet endothelial aggregation receptor 1 protein (932-1037AA)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Platelet endothelial aggregation receptor 1 (PEAR1) is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation
  • Upon platelet aggregation stimulated by physiological agonists, PEAR1 becomes tyrosine- and serine-phosphorylated; the tyrosine phosphorylation can be inhibited by eptifibatide, an aIIbbeta3 antagonist that also inhibits platelet aggregation
  • Recent studies have indicated that genetic variations in PEAR1, may be associated with enhanced agonist-induced platelet aggregation.