PIPA5112837

LIGHT Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5112837-Each-of-1 In Stock ₹ 42,497.50

PIPA5112837 - Each of 1

₹ 42,497.50

In Stock

Quantity

1

Base Price: ₹ 42,497.50

GST (18%): ₹ 7,649.55

Total Price: ₹ 50,147.05

Antigen

LIGHT

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TNFSF14

Gene Alias

CD258; Herpes virus entry mediator ligand; herpesvirus entry mediator ligand; HVEML; HVEM-L; Light; LTg; Ly113; sCD258; sLIGHT; soluble CD258; soluble LIGHT; Tnfsf14; TR2; tumor necrosis factor (ligand) superfamily, member 14; tumor necrosis factor ligand 1D; tumor necrosis factor ligand superfamily member 14; Tumor necrosis factor ligand superfamily member 14, membrane form; Tumor necrosis factor ligand superfamily member 14, soluble form; tumor necrosis factor superfamily member 14; UNQ391/PRO726

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

8740

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

Applications

ELISA, Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.

O43557

Gene Symbols

TNFSF14

Immunogen

Recombinant Human Tumor necrosis factor ligand superfamily member 14 protein (1-239AA)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms
  • Apoptosis is induced by certain cytokines including TNF (tumor necrosis factor) and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 (tumor necrosis factor receptor 1) and Fas
  • Cell death signals are transduced by death domain (DD)-containing adapter molecules and members of the ICE (interleukin-1-beta converting enzyme)/CED-3 (C
  • elegans death receptor-3) protease family
  • A novel DD-containing molecule was recently cloned from mouse, human and monkey and designated Daxx (death associated protein 6)
  • Daxx binds specifically to the Fas death domain and enhances Fas induced apoptosis and activates the Jun N-terminal kinase (JNK) pathway
  • Daxx is widely expressed in fetal and adult human and mouse tissues indicating its important function in Fas signaling pathways.