PIPA5112909
CPEB4 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5112909-Each-of-1 | In Stock | ₹ 42,497.50 |
PIPA5112909 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,497.50
GST (18%): ₹ 7,649.55
Total Price: ₹ 50,147.05
Antigen
CPEB4
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CPEB4
Gene Alias
CPEB4; Cpeb-4; CPE-binding protein 4; Cpe-bp4; cytoplasmic polyadenylation element binding protein 4; cytoplasmic polyadenylation element-binding protein 4; hCPEB-4; KIAA1673; mCPEB-4
Host Species
Rabbit
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
80315
Content And Storage
-20°C or -80°C if preferred
Form
Liquid
Applications
ELISA, Immunocytochemistry, Western Blot
Concentration
4 mg/mL
Formulation
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.
Q17RY0
Gene Symbols
CPEB4
Immunogen
Recombinant Human Cytoplasmic polyadenylation element-binding protein 4 protein (244-515AA)
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Description Sequence-specific RNA-binding protein that binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR (PubMed:24990967)
- RNA binding results in a clear conformational change analogous to the Venus fly trap mechanism (PubMed:24990967)
- Regulates activation of unfolded protein response (UPR) in the process of adaptation to ER stress in liver, by maintaining translation of CPE-regulated mRNAs in conditions in which global protein synthesis is inhibited
- Required for cell cycle progression, specifically for cytokinesis and chromosomal segregation (PubMed:26398195)
- Plays a role as an oncogene promoting tumor growth and progression by positively regulating translation of t-plasminogen activator/PLAT (PubMed:22138752)
- Stimulates proliferation of melanocytes (PubMed:27857118)
- In contrast to CPEB1 and CPEB3, does not play role in synaptic plasticity, learning and memory
- [UniProt]