ACBD3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5113338-Each-of-1 | In Stock | ₹ 43,120.50 |
PIPA5113338 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,120.50
GST (18%): ₹ 7,761.69
Total Price: ₹ 50,882.19
Antigen
ACBD3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Acbd3
Gene Alias
60kDa; 8430407O11Rik; Acbd3; acyl-CoA binding domain containing 3; acyl-CoA-binding domain-containing protein 3; acyl-Coenzyme A binding domain containing 3; D1Ertd10e; DAP; DMT1-associated protein; fa20g08; GCP60; Gocap1; golgi complex associated protein 1, 60 kDa; golgi complex associated protein 1, 60kDa; golgi complex-associated protein 1; Golgi phosphoprotein 1; Golgi resident protein GCP60; Golgi resident protein GCP60, N-terminally processed; GOLPH1; neurotrophin receptor alike death domain protein; p75-like apoptosis-inducing death domain protein; Pap7; PBR- and PKA-associated protein 7; PBR associated protein; Peripheral benzodiazepine receptor-associated protein PAP7; peripherial benzodiazepine receptor associated protein; PKA (RIalpha)-associated protein; si:dkey-267p15.1; wu:fa20g08; zgc:66303
Host Species
Rabbit
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
289312, 64746
Content And Storage
-20°C or -80°C if preferred
Form
Liquid
Applications
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
2.8 mg/mL
Formulation
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.
Q7TNY6, Q9H3P7
Gene Symbols
Acbd3
Immunogen
Recombinant Human Golgi resident protein GCP60 protein (263-366AA)
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- GOLPH1, also known as GCP60, was initially identified as a Golgi protein that can interact with the integral membrane protein giantin and is thought to be involved in the maintenance of the Golgi structure
- GOLPH1 has also been shown to interact with other Golgi proteins such as Golgin-160, a Golgi protein that can be cleaved by caspases-2, -3, and -7, leading to the nuclear localization of Golgin-160
- GOLPH1 interaction with the Golgin-160 fragments is stronger than that with the intact Golgin-160, with its interaction regulated by the oxidation state of Cys-463 within GOLPH1, suggesting that the nuclear localization of the caspase-cleaved Golgin-160 fragments is a highly coordinated event
- GOLPH1 has also been found to interact with Numb, a cytosolic signaling protein that mediates asymetric cell division of neural progenitor cells to a daughter progenitor cell and a neuron, suggesting that Golgi fragmentation and reconstitution during the cell cycle differentially regulate Numb signaling through changes in GOLPH1 subcellular distribution and may couple cell fate with cell cycle progression.