PIPA5113702

SFRS4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5113702-Each-of-1 In Stock ₹ 46,502.50

PIPA5113702 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

SFRS4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SRSF4

Gene Alias

5730499P16Rik; AW550192; MNCb-2616; Pre-mRNA-splicing factor SRP75; RGD1561347; serine and arginine rich splicing factor 4; serine/arginine-rich splicing factor 4; SFRS4; splicing factor, arginine/serine-rich 4; splicing factor, arginine/serine-rich 4 (SRp75); SR splicing factor 4; SRP001LB; SRP75; SRSF4

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

6429

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.

Q08170

Gene Symbols

SRSF4

Immunogen

Synthetic peptide directed towards the middle region of human SFRS4

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: RSREESRSRS RSRSKSERSR KRGSKRDSKA GSSKKKKKED TDRSQSRSPS For short term use, store at 2-8°C up to 1 week
  • For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles
  • Predicted homology: Dog: 93%; Human: 100%; Pig: 86%; Rat: 86% Serine/arginine-rich protein 75 (SRp75) is encoded by the SRSF4 gene
  • SRp75 belongs to the arginine/serine-rich factor family and likely plays a role in alternative mRNA splicing.The family of SR factors all contain one or more RNA recognition motifs (RRM) and an arginine/ serine (RS)-rich domain
  • They are not only essential for constitutive splicing but also regulate splicing in a concentration-dependent manner by influencing the selection of alternative splice sites
  • The majority of SR proteins, including SC35 and SRp40, are confined to the nucleus, while SF2/ASF, SRp20, and 9G8 are continuously shuttled between the nucleus and the cytoplasm and contribute to mRNA transport
  • The activity of SR proteins in regulated splicing is antagonized by members of the hnRNP A/B family of proteins, which induce drastic shifts in the selection of splicing sites.