IL-22 Receptor alpha Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5113903-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5113903 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
IL-22 Receptor alpha
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Il22ra1
Gene Alias
9130219A07Rik; CRF2-9; Cytokine receptor class-II member 9; cytokine receptor family 2 member 9; ENSMUSG00000073746; il-22 receptor; IL-22 receptor subunit alpha-1; IL22R; IL-22R; IL22R1; IL22RA1; IL-22RA1; IL-22R-alpha-1; ILN; Interleukin; interleukin 22 receptor subunit alpha 1; interleukin 22 receptor, alpha 1; interleukin-22 receptor alpha chain; interleukin-22 receptor subunit alpha-1; RGD1559655; zcytoR11
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
58985
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.
Q8N6P7
Gene Symbols
Il22ra1
Immunogen
Synthetic peptide directed towards the middle region of human IL22RA1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: DQGPSPWGLL ESLVCPKDEA KSPAPETSDL EQPTELDSLF RGLALTVQWE For short term use, store at 2-8°C up to 1 week
- For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles
- Predicted homology: Cow: 100%; Dog: 100%; Guinea Pig: 79%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 93% A novel cytokine, designated IL-TIF for IL-10 related T cell-derived inducible factor and IL-22, was recently identified
- The receptor for IL-22 (IL-22R, also termed CRF2-9 and IL-TIF-R1 chain) is a new member of the class II cytokine receptor family
- IL-22R forms a complex with IL-10 receptor beta chain and mediates IL-22 signaling
- IL-22 and its receptor activate JAK-STAT signaling pathway
- IL22R is expressed in normal liver and kidney and their cell lines HepG2 and TK-10
- A soluble form of IL-22 receptor, also termed IL-22 binding protein (IL-22BP) and IL-22 receptor-alpha 2 (IL-22RA2), was identified very recently
- IL-22BP prevents binding of IL-22 to the functional cell surface IL-22R complex and neutralizes IL-22 activity
- LPS induces IL-22 expression, which indicates the role of IL-22 in inflammatory response.