PIPA5114058

NCAPH2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5114058-Each-of-1 In Stock ₹ 46,502.50

PIPA5114058 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

NCAPH2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NCAPH2

Gene Alias

CAPH2; CAP-H2 subunit of the condensin II complex; Chromosome-associated protein H2; condensin-2 complex subunit H2; CTA-384D8.36; D15Ertd785e; hCAP-H2; kleisin beta; Kleisin-beta; Ncaph2; Non-SMC condensin II complex subunit H2; non-SMC condensin II complex, subunit H2

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

29781

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.

Q6IBW4

Gene Symbols

NCAPH2

Immunogen

Synthetic peptide directed towards the N terminal region of human NCAPH2

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: SGVPQEAENE FLSLDDFPDS RTNVDLKNDQ TPSEVLIIPL LPMALVAPDE For short term use, store at 2-8°C up to 1 week
  • For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles
  • Predicted homology: Dog: 75%; Horse: 85%; Human: 100%; Mouse: 92%; Rabbit: 92%; Rat: 92% Structural maintenance of chromosomes (SMC) and non-SMC condensin proteins associate into complexes that have been implicated in the process of chromosome condensation
  • A crucial prerequisite for accurate segregation of replicated sister chromatids is the condensation of the chromosomes into a manageable form prior to metaphase
  • The condensin I complex consists of two SMC subunits, SMC2 and SMC4, and three non-SMC subunits, CAP-H, CAP-G, and CAP-D2
  • An alternative complex, the condensin II complex, contains alternate non-SMC subunits, CAP-G2, CAP-H2, and CAP-D3
  • CAP-H2 is also known as Non-SMC condensin II complex, subunit H2 (NCAPH2) or kleisin beta isoform 2
  • The three non-SMC subunits in the condensing complexes form a regulatory subcomplex that is required to activate the SMC ATPases and to promote mitosis-specific chromatin binding of the holocomplex
  • The precise individual functions of each non-SMC protein in activation remain to be determined.