PIPA5114066
LEMD2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5114066-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5114066 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
LEMD2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
LEMD2
Gene Alias
BC026588; CTRCT42; dJ482C21.1; hLEM2; LEM domain containing 2; LEM domain-containing protein 2; Lem2; LEMD2; NET25; nuclear envelope constituent; Nuclear envelope transmembrane protein 25
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
221496
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.
Q8NC56
Gene Symbols
LEMD2
Immunogen
Synthetic peptide directed towards the middle region of human LEMD2
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: QDMERYPYVG ILHVRDSLIP PQSRRRMKRV WDRAVEFLAS NESRIQTESH For short term use, store at 2-8°C up to 1 week
- For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles
- Predicted homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 89% The LEM (lamina-associated polypeptide-emerin-MAN1) domain is a motif shared by a group of lamin-interacting proteins of the inner nuclear membrane (INM) and nucleoplasm
- One such protein, LEMD2 (LEM domain-containing protein 2), is a lamina-associated protein in the INM involved in nuclear structure organization, containing an N-terminal LEM motif, two transmembrane domains, and a MAN1-Src1p C-terminal (MSC) domain
- LEMD2 is a truncated paralog of MAN1, lacking the MAN1-specific C-terminal RNA-recognition motif, but like MAN1 is required for myogenic differentiation
- Mutations in LEMD2 are thought be among the possible causes of muscle disease.