PIPA5114150
GCH1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5114150-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5114150 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
GCH1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GCH1
Gene Alias
dystonia 14; DYT14; DYT5; DYT5a; GCH; Gch1; GTP cyclohydrolase 1; GTP cyclohydrolase I; GTPCH; GTP-CH; GTPCH1; GTP-CH-1; GTP-CH-I; guanosine 5'-triphosphate cyclohydrolase I; HPABH4B
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
2643
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.
P30793
Gene Symbols
GCH1
Immunogen
Synthetic peptide directed towards the N-terminal region of Human GCH1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: PPRPEAKSAQ PADGWKGERP RSEEDNELNL PNLAAAYSSI LSSLGENPQR For short term use, store at 2-8°C up to 1 week
- For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles
- Predicted homology: Cow: 100%; Dog: 100%; Human: 100%; Rabbit: 100%; Rat: 86% This gene encodes a member of the GTP cyclohydrolase family
- The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate
- BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases
- Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia
- Several alternatively spliced transcript variants encoding different isoforms have been described; however, not all variants give rise to a functional enzyme.