Caspase 7 (Cleaved Asp198) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5114688-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5114688 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Caspase 7 (Cleaved Asp198)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CASP7
Gene Alias
AI314680; Apoptotic protease Mch-3; Casp7; CASP-7; caspase 7; caspase 7 isoform delta; caspase 7, apoptosis-related cysteine peptidase; caspase 7, apoptosis-related cysteine protease; caspase-7; Caspase-7 subunit p11; Caspase-7 subunit p20; CMH-1; Cysteine protease LICE2; ICE-IAP3; ICE-LAP3; ICE-like apoptotic protease 3; Lice2; Lice2 alpha/beta/gamma; mCASP-7; MCH3; OTTHUMP00000020511; OTTHUMP00000020513; OTTHUMP00000020514
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
12369, 840
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.
P55210, P97864
Gene Symbols
CASP7
Immunogen
A synthesized peptide derived from human CASP7(Accession P55210), corresponding to amino acid residues P178-A207.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of fragment of activated Caspase 7 resulting from cleavage adjacent to Asp198
- Caspase 7 is part of a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies
- Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens
- The apoptotic subfamily can be further divided into initiator caspases, which are activated in response to death signals, and executioner caspases, which are activated by the initiator caspases and are responsible for cleavage of cellular substrates that μgtimately lead to cell death
- Caspase 7 is an executioner caspase that was identified based on its homology with caspases 1 and 3, as well as the C
- elegans cell death protein CED-3
- Alternative splicing of Caspase-7 mRNA results in the production of 3 distinct isoforms
- Caspase-7 activity can be directly inhibited by XIAP expression
- Alternative splicing results in four transcript variants, encoding three distinct isoforms of Caspase 7
- Diseases associated with CASP7 include Type 1 Diabetes Mellitus 17 and Aleutian Mink Disease.