BRUCE Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5114907-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5114907 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
BRUCE
Classification
Polyclonal
Conjugate
Unconjugated
Gene
BIRC6
Gene Alias
A430032G04Rik; A430040A19Rik; AA501170; APOLLON; baculoviral IAP repeat containing 6; baculoviral IAP repeat-containing 6; baculoviral IAP repeat-containing protein 6; baculovirus inhibitor of apoptosis repeat containing ubiquitin-conjugating enzyme; baculovirus inhibitor of apoptosis repeat containing ubiquitin-conjugating enzyme; accccbaculoviral IAP repeat-containing 6; BIR repeat-containing ubiquitin-conjugating enzyme; Birc6; BRUCE; D630005A10Rik; KIAA1289; mKIAA1289; RING-type E3 ubiquitin transferase BIRC6; Ubiquitin-conjugating BIR domain enzyme apollon; ubiquitin-conjugating BIR-domain enzyme apollon
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
12211, 57448
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.
O88738, Q9NR09
Gene Symbols
BIRC6
Immunogen
A synthesized peptide derived from human BIRC6(Accession Q9NR09), corresponding to amino acid residues L4692-E4742.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total BIRC6
- Apoptosis, or programmed cell death, is related to many diseases, such as cancer
- Apoptosis is triggered by a variety of stimuli including members in the TNF family and can be prevented by the inhibitor of apoptosis (IAP) proteins
- IAP proteins form a conserved gene family that binds to and inhibits cell death proteases
- BRUCE, also known as BIRC6, is an IAP family member protein with a BIR (baculoviral inhibition of apoptosis protein repeat) domain and a UBCc (ubiquitin-conjugating enzyme E2, catalytic) domain
- BRUCE regulates p53 and the mitochondrial pathway of apoptosis by facilitating the degradation of apoptotic proteins such as Caspase-9 and SMAC by ubiquitination.