PIPA5115057

Cystatin 2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5115057-Each-of-1 In Stock ₹ 46,502.50

PIPA5115057 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

Cystatin 2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CST2

Gene Alias

CST2; cystatin 2; cystatin S5; cystatin SA; cystatin-2; Cystatin-S5; cystatin-SA; cysteine-proteinase inhibitor; salivary cysteine (thiol) protease inhibitor

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1470

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.

P09228

Gene Symbols

CST2

Immunogen

A synthesized peptide derived from human CST2(Accession P09228), corresponding to amino acid residues C6-N56.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total CST2
  • The cystatin superfamily is a well-established family of cysteine protease inhibitors
  • Cystatins A and B (type 1) are mainly intracellular; cystatins C, D, E/M, F, G, S, SN and SA cystatins are extracellular (type 2); and the kininogens are type 3 cystatins which are intravascular proteins
  • All true cystatins inhibit cysteine peptidases of the papain family, such as cathepsins, and some also inhibit legumain family enzymes
  • Cystatin SA, cystatin S and cystatin SN are found primarily in saliva
  • Cystatin S and SN can also be expressed in tears, urine and seminal fluid
  • Cystatin C is a related protein which is expressed in brain, thymus, ovary, epididymis and vas deferens
  • Cystatin D protects against proteinases in the oral cavity, while Cystatin E/M and F moderate the inhibition of cathepsin proteins
  • The fetuins, part of the cystatin superfamily, are secretable proteins that influence osteogenesis and bone resorption, regulation of the insulin and hepatocyte growth factor receptors and the response to systemic inflammation
  • High molecular weight kininogen (Kininogen HC) and low molecular weight kininogen (Kininogen LC) have varied roles, though they both inhibit the thrombin- and plasmin-induced aggregation of thrombocytes.