HAAO Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5115337-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5115337 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
HAAO
Classification
Polyclonal
Conjugate
Unconjugated
Gene
HAAO
Gene Alias
0610007K21Rik; 0610012J07Rik; 3HAO; 3-HAO; 3-HAO {ECO:0000255; 3-HAOxase; 3-hydroxyanthranilate 3,4-dioxygenase; 3-hydroxyanthranilate 3,4-dioxygenase {ECO:0000255; 3-hydroxyanthranilate oxygenase; 3-hydroxyanthranilate oxygenase {ECO:0000255; 3-hydroxyanthranilic acid dioxygenase; 3-hydroxyanthranilic acid dioxygenase {ECO:0000255; Haao; HAD; HAD {ECO:0000255; HAMAP-Rule:MF_03019}; HAO
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
107766, 23498, 56823
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.
P46952, P46953, Q78JT3
Gene Symbols
HAAO
Immunogen
A synthesized peptide derived from human HAAO(Accession P46952), corresponding to amino acid residues L141-H191.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total HAAO
- HAAO (3-Hydroxyanthranilate 3, 4-dioxygenase) is a monomeric cytosolic protein of the family of intramolecular dioxygenases containing non-heme ferrous iron
- It is widely distributed in peripheral organs, such as liver and kidney, and is present in low amounts in the central nervous system
- This enzyme participates in tryptophan metabolism
- It employs one cofactor, iron
- HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid
- QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors
- Increased cerebral levels of QUIN may participate in the pathogenesis of neurological and inflammatory disorders
- HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN
- Furthermore, recent study shows that HAAO are excellent candidate biomarkers for detecting ovarian cancer.