P2X2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5115706-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5115706 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
P2X2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
P2RX2
Gene Alias
ATP receptor; DFNA41; MGC129601; P2RX2; P2X purinoceptor 2; P2X Receptor, subunit 2; P2X2; P2X2 purinoceptor; P2X2 receptor splice variant P2X2-1; P2X2 receptor splice variant P2X2-2; P2X2 receptor splice variant P2X2-3; P2X2a; Purinergic receptor; purinergic receptor P2X 2; purinergic receptor P2X, ligand gated ion channel, 2; purinergic receptor P2X, ligand-gated ion channel, 2; purinergic receptor P2X2
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
22953, 231602
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.
Q8K3P1, Q9UBL9
Gene Symbols
P2RX2
Immunogen
A synthesized peptide derived from human P2RX2(Accession Q9UBL9), corresponding to amino acid residues H408-Q458.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total P2X2
- P2rx2 are members of the ligand-gated ion channel family that open in response to extracellular ATP
- Each receptor is made up of a trimer of subunits (P2X1-7) all of which share the common structure of two transmembrane domains
- P2rx2 functions as a ligand-gated ion channel and binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle
- Six transcript variants encoding six distinct isoforms have been identified for P2rx2
- P2rx2 is involved in a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis
- In the inner ear, P2rx2 regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling
- P2rx2 also mediates synaptic transmission between neurons and from neurons to smooth muscle
- Diseases associated with P2RX2 include Deafness, Autosomal Dominant 41 and Dfna41 Nonsyndromic Hearing Loss And Deafness.