CALM Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5115756-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5115756 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
CALM
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Picalm
Gene Alias
CALM; Clathrin assembly lymphoid myeloid leukemia; clathrin assembly lymphoid myeloid leukemia protein; clathrin-assembly lymphoid leukemia protein; clathrin-assembly lymphoid myeloid leukemia protein; CLTH; fit1; fit-1; LAP; mKIAA4114; PAP180; phosphatidylinositol binding clathrin assembly protein; phosphatidylinositol-binding clathrin assembly protein; PICALM; rCALM
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
233489, 8301, 89816
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.
O55012, Q13492, Q7M6Y3
Gene Symbols
Picalm
Immunogen
A synthesized peptide derived from human PICALM(Accession Q13492), corresponding to amino acid residues M617-M652.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total PICALM
- PICALM, also known as the clathrin assembly lymphoid myeloid leukemia (CALM) protein, co-localizes with clathrin at clathrin-coated areas of the plasma membrane and in the Golgi area, and is thought to be an important component of the coated pit internalization machinery
- Fusion proteins involving PICALM have been implicated in acute myeloid and T-cell acute lymphoblastic leukemia
- PICALM is also expressed in neurons and is present at the synapse where it facilitates the endocytosis of the synaptic vesicle protein VAMP2
- Recent studies have identified variants of PICALM associated with Alzheimer's disease and have suggested this protein may play a role in the endocytosis and recycling of the amyloid protein precursor (APP).