PCBP1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5116514-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5116514 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
PCBP1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PCBP1
Gene Alias
[a]CP-1; Alpha-CP1; alphaCP-1; epididymis secretory protein Li 85; HEL-S-85; Heterogeneous nuclear ribonucleoprotein E1; heterogenous nuclear ribonucleoprotein E1; heterogenous nuclear ribonucleoprotein X; hnRNP E1; hnRNP-E1; hnRNP-E1 protein; hnRNP-X; HNRPE1; HNRPX; Nucleic acid-binding protein SUB2.3; PCBP1; poly(rC) binding protein 1; poly(rC)-binding protein 1; RGD1561319; WBP17
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
23983, 500242, 5093
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1.01 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
P60335, Q15365
Gene Symbols
PCBP1
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human hnRNP E1/hnRNP E1/PCBP1 (NP_0061872)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: NIH/3T3, HepG2, MCF7, Mouse liver, Rat liver Immunogen sequence: LRLVVPATQC GSLIGKGGCK IKEIRESTGA QVQVAGDMLP NSTERAITIA GVPQSVTECV KQICLVMLET LSQSPQGRVM TIPYQPMPAS SPVICAGGQD R This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA
- This gene and PCBP-2 have paralogues which are thought to have arisen as a result of duplication events of entire genes
- The protein encoded by this gene appears to be multifunctional
- It along with PCBP-2 and hnRNPK corresponds to the major cellular polydomains which may be involved in RNA binding
- This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure
- It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA
- The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.