SRPX Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5116545-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5116545 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
SRPX
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SRPX
Gene Alias
down-regulated by v-src; Drs; DRS protein; drs-1; drs-2; epididymis secretory sperm binding protein Li 83p; ETX1; HEL-S-83p; mDRS-1; mDRS-2; SRPX; SRPX1; sushi repeat containing protein, X-linked; sushi repeat-containing protein SRPX; sushi-repeat containing protein, X-linked; sushi-repeat-containing protein; sushi-repeat-containing protein SRPX; sushi-repeat-containing protein X chromosome; sushi-repeat-containing protein, X chromosome; sushi-repeat-containing protein, X-chromosome; sushi-repeat-containing protein, X-linked
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
51795
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1.98 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q9R0M3
Gene Symbols
SRPX
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 40-320 of human SRPX (NP_0062981)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: Mouse heart, Mouse liver Immunogen sequence: EDDEVGYSHP RYKDTPWCSP IKVKYGDVYC RAPQGGYYKT ALGTRCDIRC QKGYELHGSS LLICQSNKRW SDKVICKQKR CPTLAMPANG GFKCVDGAYF NSRCEYYCSP GYTLKGERTV TCMDNKAWSG RPASCVDMEP PRIKCPSVKE RIAEPNKLTV RVSWETPEGR DTADGILTDV ILKGLPPGSN FPEGDHKIQY TVYDRAENKG TCKFRVKVRV KRCGKLNAPE NGYMKCSSDG DNYGATCEFS CIGGYELQGS PARVCQSNLA WSGTEPTCAA M SRPX1 was initially identified as a candidate gene for X-linked retinitis pigmentosa and is overexpressed in the trabecular network of the eye in glaucoma conditions
- Its expression is significantly downregulated in a number cancer cell lines and malignant tumor tissues and its ectopic expression induces apoptosis through the endoplasmic reticulum and the activation of caspase-12, -9, and -3, indicating that it can function as a tumor suppressor
- SRPX1 is also involved with the regulation of autophagy under low serum conditions and can associate with Rab24, a member of the Rab GTPase protein family that is involved in autophagy
- This association of SRPX1 with Rab24 is enhanced during autophagy.