RNF185 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5116662-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5116662 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
RNF185
Classification
Polyclonal
Conjugate
Unconjugated
Gene
RNF185
Gene Alias
BSK65-MONO1; BSK65-MONO2; BSK65-PANC1; BSK65-PANC2; BSK65-TEST1; BSK65-TEST2; BSK65-TEST3; E3 ubiquitin-protein ligase RNF185; FLJ38628; I79_017427; ring finger protein 185; RING-type E3 ubiquitin transferase RNF185; rn185; Rnf185
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
193670, 360967, 91445
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
1.33 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.
Q568Y3, Q91YT2, Q96GF1
Gene Symbols
RNF185
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human RNF185 (NP_6894802)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: Mouse testis Immunogen sequence: MASKGPSASA SPENSSAGGP SGSSNGAGES GGQDSTFECN ICLDTAKDAV ISLCGHLFCW PCLHQWLETR PNRQVCPVCK AGISRDKVIP LYGRGSTGQQ DPREKTPPRP QGQRPEPENR GGFQGFGFGD RNF185 is a E3 ubiquitin-protein ligase that regulates selective mitochondrial autophagy by mediating Lys-63-linked polyubiquitination of BNIP1
- RNF185 acts in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway, which targets misfolded proteins that accumulate in the endoplasmic reticulum (ER) for ubiquitination and subsequent proteasome-mediated degradation
- RNF185 protects cells from ER stress-induced apoptosis
- is responsible for the cotranslational ubiquitination and degradation of CFTR in the ERAD pathway, and is preferentially associates with the E2 enzymes UBE2J1 and UBE2J2.