CPSF1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5116722-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5116722 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
CPSF1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Cpsf1
Gene Alias
cleavage and polyadenylation specific factor 1; cleavage and polyadenylation specific factor 1, 160kDa; cleavage and polyadenylation specificity factor 1; cleavage and polyadenylation specificity factor 160 kDa subunit; Cleavage and polyadenylation specificity factor subunit 1; CPSF 160 kDa subunit; CPSF1; CPSF160; HSU37012; P/cl.18; polyadenylation specificity factor
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
29894, 94230
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
1.65 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.
Q10570, Q9EPU4
Gene Symbols
Cpsf1
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 700-950 of human CPSF1 (NP_0374232)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: 293T, NIH/3T3, Mouse liver Immunogen sequence: LYRDLSGMFT TESRLGGARD ELGGRSGPEA EGLGSETSPT VDDEEEMLYG DSGSLFSPSK EEARRSSQPP ADRDPAPFRA EPTHWCLLVR ENGTMEIYQL PDWRLVFLVK NFPVGQRVLV DSSFGQPTTQ GEARREEATR QGELPLVKEV LLVALGSRQS RPYLLVHVDQ ELLIYEAFPH DSQLGQGNLK VRFKKVPHNI NFREKKPKPS KKKAEGGGAE EGAGARGRVA RFRYFEDIYG YSGVFICGPS P Midline-1 (Tripartite motif-containing protein 18, Putative transcription factor XPRF, RING finger protein 59) is a 667 amino acid protein encoded by the human gene MID1
- Midline-1 belongs to the TRIM/RBCC family and contains two B box-type zinc fingers, one B30.2/SPRY domain, one COS domain, one fibronectin type-III domain and one RING-type zinc finger
- Midline-1 is believed to have E3 ubiquitin ligase activity which targets the catalytic subunit of protein phosphatase 2 for degradation
- It is a cytoplasmic protein found as a homodimer or heterodimer with Midline-2
- It also interacts with IGBP1 (Lymphocyte signaling protein A4)
- Defects in MID1 are the cause of Opitz syndrome type I (OS-I)
- OS-I is an X-linked recessive disorder characterized by hypertelorism, genital-urinary defects such as hypospadias in males and splayed labia in females, lip-palate-laryngotracheal clefts, imperforate anus, developmental delay and congenital heart defects.