PIPA5116762

Calpain 7 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5116762-Each-of-1 In Stock ₹ 46,502.50

PIPA5116762 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

Calpain 7

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CAPN7

Gene Alias

AU022319; calpain 7; calpain like protease; CALPAIN7; calpain-7; Capn7; homolog of Aspergillus Nidulans PALB; palB homolog; PALBH

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12339, 23473, 306260

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

2.36 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.

Q9R1S8, Q9Y6W3

Gene Symbols

CAPN7

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 20-220 of human CAPN7 (NP_0551111)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Samples: Jurkat Immunogen sequence: RDHEGRYSEA VFYYKEAAQA LIYAEMAGSS LENIQEKITE YLERVQALHS AVQSKSADPL KSKHQLDLER AHFLVTQAFD EDEKENVEDA IELYTEAVDL CLKTSYETAD KVLQNKLKQL ARQALDRAEA LSEPLTKPVG KISSTSVKPK PPPVRAHFPL GANPFLERPQ SFISPQSCDA QGQRYTAEEI EVLRTTSKIN G Calpain proteinases are defined currently as papain-like neutral proteases that are calcium activated
  • Calpains 1 and 2 are composed of a large subunit, which is proteolytically active, and a small subunit (also called calpain-4), or enhancer protein, that is not proteolytically active
  • The other calpain proteins identified to date (calpain 5, 6, 8, 9, 10, 11, 12, 13, 14, 15) are not known to require a small subunit
  • Domains in the large subunit include the amino terminal domain-I, the proteinase domain-II, domain-III, and the EF-hand domain-IV (domain-T in calpains 5 & 6, domain-N for calpain-7)
  • Calpain-7 domain-N does not have the standard calpain EF hand domain for binding calcium, making it unclear whether it is calcium regulated
  • In place of the EF hand calcium-binding domain IV, calpain-7 has a sequence most closely resembling domain-III, with unknown function
  • Calpain-7 is widely distributed, found in most tissues analyzed.