ZDHHC2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5116793-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5116793 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
ZDHHC2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ZDHHC2
Gene Alias
5730415P04Rik; 6430583A19Rik; DHHC2; DHHC-2; membrane-associated DHHC2 zinc finger protein; palmitoyltransferase ZDHHC2; Ream; rec; Reduced expression associated with metastasis protein; reduced expression in cancer protein; small rec; srec; testis tissue sperm-binding protein Li 56e; Zdhhc2; Zinc finger DHHC domain-containing protein 2; zinc finger DHHC-type containing 2; zinc finger protein 372; zinc finger, DHHC domain containing 2; zinc finger, DHHC-type containing 2; ZNF372
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
246326, 51201
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
1.3 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.
Q9JKR5, Q9UIJ5
Gene Symbols
ZDHHC2
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 270-367 of human ZDHHC2 (NP_0574371)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: BxPC-3, Rat lung Immunogen sequence: QVFGDEKKYW LLPIFSSLGD GCSFPTCLVN QDPEQASTPA GLNSTAKNLE NHQFPAKPLR ESQSHLLTDS QSWTESSINP GKCKAGMSNP ALTMENET Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates and is involved in a variety of cellular processes (PubMed:18508921, PubMed:18296695, PubMed:19144824, PubMed:21343290, PubMed:22034844, PubMed:23793055)
- In the nervous system, plays a role in long term synaptic potentiation by palmitoylating AKAP5 through which it regulates protein trafficking from the dendritic recycling endosomes to the plasma membrane and controls both structural and functional plasticity at excitatory synapses
- In dendrites, mediates the palmitoylation of DLG4 when synaptic activity decreases and induces synaptic clustering of DLG4 and associated AMPA-type glutamate receptors
- Also mediates the de novo and turnover palmitoylation of RGS7BP, a shuttle for Gi/o-specific GTPase-activating proteins/GAPs, promoting its localization to the plasma membrane in response to the activation of G protein-coupled receptors
- Through the localization of these GTPase-activating proteins/GAPs, it also probably plays a role in G protein-coupled receptors signaling in neurons
- Also probably plays a role in cell adhesion by palmitoylating CD9 and CD151 to regulate their expression and function (PubMed:18508921)
- Palmitoylates the endoplasmic reticulum protein CKAP4 and regulates its localization to the plasma membrane (PubMed:18296695, PubMed:19144824)
- Could also palmitoylate LCK and regulate its localization to the plasma membrane (PubMed:22034844)
- [UniProt]