TOPORS Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5116849-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5116849 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
TOPORS
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TOPORS
Gene Alias
AW105885; E3 ubiquitin-protein ligase Topors; LUN; p53-binding protein 3; P53BP3; p53BP3/LUN; RING-type E3 ubiquitin transferase Topors; RP31; SUMO1-protein E3 ligase Topors; TOP1 binding arginine/serine rich protein; topoisomerase 1-binding RING finger; topoisomerase I binding, arginine/serine-rich; topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase; topoisomerase I-binding arginine/serine-rich protein; Topoisomerase I-binding RING finger protein; Topors; TP53BPL; tumor suppressor p53-binding protein 3
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
106021, 362501
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
1.4 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.
Q80Z37
Gene Symbols
TOPORS
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 100-200 of mouse Topors (NP_5988582)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: Mouse liver, Mouse lung, Mouse kideny, Rat kidney Immunogen sequence: PDSKCPICLD RFDNVSYLDR CLHKFCFRCV QEWSKNKAEC PLCKQPFDSI FHSVRAEDDF KEYVLRPSYN GSFTNPEVRR FRYRTTMTRE RSASLYSPSS T Functions as an E3 ubiquitin-protein ligase and as an E3 SUMO1-protein ligase
- Probable tumor suppressor involved in cell growth, cell proliferation and apoptosis that regulates p53/TP53 stability through ubiquitin-dependent degradation
- May regulate chromatin modification through sumoylation of several chromatin modification-associated proteins
- May be involved in DNA damage-induced cell death through IKBKE sumoylation.