PIPA5116855
TMEM18 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5116855-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5116855 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
TMEM18
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TMEM18
Gene Alias
BC024093; TMEM18; Transmembrane protein 18
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
129787, 362722
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
1.33 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.
Q6DGF8, Q96B42
Gene Symbols
TMEM18
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 40-100 of human TMEM18 (NP_6900472)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: HeLa, A-549, Rat kidney Immunogen sequence: LLTCLSSRSY RLQIGHFLCL VILVYCAEYI NEAAAMNWRL FSKYQYFDSR GMFISIVFSA P Recent studies have examined how overexpression of certain genes enhances the tropism of neural stem cells (NSCs) for gliomas
- Overexpression of Transmembrane protein 18 (TMEM18) provides NSCs and neural precursors an increased migration capacity towards glioblastoma cells in vitro and in the rat brain, while functional inactivation of the gene resulted in an almost complete loss of migration activity, suggesting that TMEM18 could be a potential target in NSC-based glioma therapy
- Other recent results suggest that among others, the TMEM18 loci is associated with higher than normal body mass index (BMI) and obesity, indicating there may be a CNS-related role in predisposition to obesity
- Multiple isoforms of TMEM18 are known to exist.