PIPA5116946

SARS-CoV-2 ORF3a Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5116946-Each-of-1 In Stock ₹ 46,502.50

PIPA5116946 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

SARS-CoV-2 ORF3a

Classification

Polyclonal

Conjugate

Unconjugated

Gene Alias

COVID19 ORF3A; COVID-19 ORF3A; ORF3A; SARS-CoV-2 Open Reading Frame 3A; SARS-COV2 ORF3A

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 100-200 of coronavirus ORF3A (YP_0097243911)

Quantity

100 μL

Primary or Secondary

Primary

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.66 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Target Species

Virus

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Samples: 293T Immunogen sequence: GDGTTSPISE HDYQI ORF3A forms homotetrameric potassium sensitive ion channels (viroporin) and may modulate virus release
  • Up-regulates expression of fibrinogen subunits FGA, FGB and FGG in host lung epithelial cells
  • Induces apoptosis in cell culture
  • Downregulates the type 1 interferon receptor by inducing serine phosphorylation within the IFN alpha-receptor subunit 1 (IFNAR1) degradation motif and increasing IFNAR1 ubiquitination.