JNK3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5116957-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5116957 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
JNK3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MAPK10
Gene Alias
C230008H04Rik; c-Jun N-terminal kinase 3; hypothetical protein LOC569698; jnk3; JNK3 alpha protein kinase; JNK3 beta1 protein kinase; JNK3 beta2 protein kinase; JNK3A; JNK3B1; JNK3B2; MAP kinase 10; MAP kinase p49 3F12; MAPK 10; MAPK10; mitogen activated protein kinase 10; mitogen-activated protein kinase 10; OTTHUMP00000161181; OTTHUMP00000161183; OTTHUMP00000218718; p493F12; p54-beta; p54bSAPK; PRKM10; SAPb; SAPK(beta); SAPK/Erk/kinase 2; SAPK1B; SAPK-beta; SAPKC; Serk2; Stress activated protein kinase beta; stress-activated protein kinase 1b; Stress-activated protein kinase JNK3; zgc:123234
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
26414
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.52 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q61831
Gene Symbols
MAPK10
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 175-464 of human JNK3 (NP_6204481)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: Mouse brain, Mouse testis Immunogen sequence: CGIKHLHSAG IIHRDLKPSN IVVKSDCTLK ILDFGLARTA GTSFMMTPYV VTRYYRAPEV ILGMGYKENV DIWSVGCIMG EMVRHKILFP GRDYIDQWNK VIEQLGTPCP EFMKKLQPTV RNYVENRPKY AGLTFPKLFP DSLFPADSEH NKLKASQARD LLSKMLVIDP AKRISVDDAL QHPYINVWYD PAEVEAPPPQ IYDKQLDERE HTIEEWKELI YKEVMNSEEK TKNGVVKGQP SPSGAAVNSS ESLPPSSSVN DISSMSTDQT LASDTDSSLE ASAGPLGCCR MAPK10 (JNK3) is a neuronal-specific form of c-Jun N-terminal kinases (JNKs)
- MAPK10 is involved in neuronal apoptosis and phosphorylates MAP2K4
- MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development
- This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs)
- Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis
- Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (NhpK4)
- Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis
- Four alternatively spliced transcript variants encoding distinct isoforms have been reported.