SF3A1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5117000-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5117000 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
SF3A1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Sf3a1
Gene Alias
1200014H24Rik; 5930416L09Rik; AI159724; pre-mRNA processing 21; pre-mRNA splicing factor SF3a (120 kDa subunit); PRP21; PRPF21; SAP 114; SAP114; Sf3a1; sf3a1 protein; SF3A120; si:dz150f13.2; spliceosome-associated protein 114; splicing factor 3 subunit 1; splicing factor 3A subunit 1; splicing factor 3a, subunit 1; splicing factor 3a, subunit 1, 120kD; splicing factor 3a, subunit 1, 120kDa; Unknown (protein for MGC:65786); wu:fc38e01; wu:fc50a11; wu:fj37c05; zgc:65786
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
305479, 67465
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
2.21 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.
Q8K4Z5
Gene Symbols
Sf3a1
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 715-785 of human SF3A1 (Q15459)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: Mouse lung, Rat brain, Rat lung Immunogen sequence: QDKTEWKLNG QVLVFTLPLT DQVSVIKVKI HEATGMPAGK QKLQYEGIFI KDSNSLAYYN MANGAVIHLA L This gene encodes subunit 1 of the splicing factor 3a protein complex
- The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing
- Subunit 1 belongs to the SURP protein family; named for the SURP motifs that are thought to mediate RNA binding
- Subunit 1 has tandemly repeated SURP motifs in its amino-terminal half while its carboxy-terminal half contains a proline-rich region and a ubiquitin-like domain
- Binding studies with truncated subunit 1 derivatives demonstrated that the two SURP motifs are necessary for binding to subunit 3 while contacts with subunit 2 may occur through sequences carboxy-terminal to the SURP motifs
- Alternative splicing results in multiple transcript variants encoding different isoforms.