MA2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5117001-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5117001 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
MA2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PNMA2
Gene Alias
40 kDa neuronal protein; A830049P17Rik; KIAA0883; MA2; mKIAA0883; MM2; onconeuronal antigen MA2; Paraneoplastic antigen Ma2; paraneoplastic antigen Ma2 homolog; paraneoplastic Ma antigen 2; paraneoplastic neuronal antigen MM2; Pnma2; retrotransposon gag domain containing 2; RGAG2
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10687, 305977
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
3.26 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.
Q9UL42
Gene Symbols
PNMA2
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human PNMA2 (NP_0091881)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: 293T, Jurkat, Rat brain Immunogen sequence: MALALLEDWC RIMSVDEQKS LMVTGIPADF EEAEIQEVLQ ETLKSLGRYR LLGKIFRKQE NANAVLLELL EDTDVSAIPS EVQGKGGVWK VIFKTPNQDT EFLERLNLFL EKEGQTVSGM FRALGQEGVS PATVPCISPE In patients with cancer, symptoms of limbic and brain-stem dysfunction may result from a para-neoplastic disorder
- Two proteins, Ma1 and Ma2, were discovered by presence of autoantibodies against them
- Antibodies to Ma1 and Ma2 proteins identify a paraneoplastic disorder that affects the limbic system, brain stem, and cerebellum
- These autoantibodies were used to clone Ma2, which codes for a protein (Ma2) that was recognized by serum from the 10 patients, but not by serum from 344 control subjects
- Ma2 was selectively expressed by normal brain tissue and by the testicular tumors of the patients
- Ma2 shares homology with Ma1, a "ebrain-testis-cancer"e gene related to other para-neoplastic syndromes and tumors.