UBE2C Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5117019-Each-of-1 | In Stock | ₹ 48,193.50 |
PIPA5117019 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,193.50
GST (18%): ₹ 8,674.83
Total Price: ₹ 56,868.33
Antigen
UBE2C
Classification
Polyclonal
Conjugate
Unconjugated
Gene
UBE2C
Gene Alias
(E3-independent) E2 ubiquitin-conjugating enzyme C; 1110015A16Rik; cyclin-selective ubiquitin carrier protein; D2Ertd695e; dJ447F3.2; E2 ubiquitin-conjugating enzyme C; mitotic-specific ubiquitin-conjugating enzyme; RP3-447F3.1; ubcH10; UBE2C; Ubiquitin carrier protein C; ubiquitin conjugating enzyme E2 C; ubiquitin conjugating enzyme E2C; ubiquitin-conjugating enzyme E2 C; ubiquitin-conjugating enzyme E2C; ubiquitin-protein ligase C
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
11065, 296368, 68612
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration
0.50 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.
O00762, Q9D1C1
Gene Symbols
UBE2C
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-179 of human UBE2C (NP_0089501)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: 22Rv1, THP-1, U-87MG, SW620, SKOV3 Immunogen sequence: MASQNRDPAA TSVAAARKGA EPSGGAARGP VGKRLQQELM TLMMSGDKGI SAFPESDNLF KWVGTIHGAA GTVYEDLRYK LSLEFPSGYP YNAPTVKFLT PCYHPNVDTQ GNICLDILKE KWSALYDVRT ILLSIQSLLG EPNIDSPLNT HAAELWKNPT AFKKYLQETY SKQVTSQEP This gene encodes a member of the E2 ubiquitin-conjugating enzyme family
- The encoded protein is required for the destruction of mitotic cyclins and for cell cycle progression, and may be involved in cancer progression
- Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins
- In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination
- Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis
- Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit.