GNA13 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5117026-Each-of-1 | In Stock | ₹ 47,392.50 |
PIPA5117026 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,392.50
GST (18%): ₹ 8,530.65
Total Price: ₹ 55,923.15
Antigen
GNA13
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GNA13
Gene Alias
AU024132; AU043124; G alpha 13; G alpha-13; G protein subunit alpha 13; G13; Galpha 13; Galpha13; Gna13; Gna-13; G-protein subunit alpha-13; guanine nucleotide binding protein (G protein), alpha 13; guanine nucleotide binding protein, alpha 13; guanine nucleotide-binding protein subunit alpha-13
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10672, 14674, 303634
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
2.92 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
P27601, Q14344, Q6Q7Y5
Gene Symbols
GNA13
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human GNA13 (NP_0065632)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: 293T, BT-474, Jurkat, Mouse kidney, Mouse lung, Mouse spleen, Rat kidney Immunogen sequence: MADFLPSRSV LSVCFPGCLL TSGEAEQQRK SKEIDKCLSR EKTYVKRLVK ILLLGAGESG KSTFLKQMRI IHGQDFDQRA REEFRPTIYS NVIKGMRVLV DAREKLHIPW GDNSNQQHGD KMMSFDTRAP MAAQGMVETR VFLQYLPAIR ALWADSGIQN AYDRRREFQL GESVKYFLDN LDKLGEPDYI PSQQDILLAR RPTKGIHEYD Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems (PubMed:15240885, PubMed:16787920, PubMed:16705036, PubMed:27084452)
- Activates effector molecule RhoA by binding and activating RhoGEFs (ARHGEF1/p115RhoGEF, ARHGEF11/PDZ-RhoGEF and ARHGEF12/LARG) (PubMed:15240885, PubMed:12515866)
- GNA13-dependent Rho signaling subsequently regulates transcription factor AP-1 (activating protein-1)
- Promotes tumor cell invasion and metastasis by activating RhoA/ROCK signaling pathway (PubMed:16787920, PubMed:16705036, PubMed:27084452)
- Inhibits CDH1-mediated cell adhesion in process independent from Rho activation (PubMed:11976333)
- [UniProt]