PIPA5117117
CD6 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5117117-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5117117 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
CD6
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CD6
Gene Alias
Cd6; CD6 antigen; CD6 antigen, Tp120; Cd6 molecule; FLJ44171; OX52; Soluble CD6; T12; T-cell differentiation antigen CD6; TP120
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
923
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.6 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
P30203
Gene Symbols
CD6
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 424-668 of human CD6 (NP_0067163)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: MCF7, Jurkat, U-937, HT-29, Raji Immunogen sequence: LRIKGKYALP VMVNHQHLPT TIPAGSNSYQ PVPITIPKEV FMLPIQVQAP PPEDSDSGSD SDYEHYDFSA QPPVALTTFY NSQRHRVTDE EVQQSRFQMP PLEEGLEELH ASHIPTANPG HCITDPPSLG PQYHPRSNSE SSTSSGEDYC NSPKSKLPPW NPQVFSSERS SFLEQPPNLE LAGTQPAFSA GPPADDSSST SSGEWYQNFQ PPPQPPSEEQ FGCPGSPSPQ PDSTDNDDYD DISAA CD6, also known as T12, is a member of the scavenger receptor superfamily found on T and B cell subsets, thymocytes, and acute lymphocytic leukemia cells (ALL)
- CD6 interacts with its ligand CD166/ALCAM (activated leukocyte cell adhesion molecule) and serves as a coreceptor for T cell activation and stabilizer of the immunological synapse
- CD6-ALCAM mediated cell adhesion is also important for T cell proliferation
- CD6 may exert some its functions via association with CD5, probably by fine-tuning CD5 signaling
- Ligation of CD6 has antiapoptotic role in chronic lymphocytic leukemia B cells.