PIPA5117255

Phospho-Cdc25A (Ser76) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5117255-Each-of-1 In Stock ₹ 47,392.50

PIPA5117255 - Each of 1

₹ 47,392.50

In Stock

Quantity

1

Base Price: ₹ 47,392.50

GST (18%): ₹ 8,530.65

Total Price: ₹ 55,923.15

Antigen

Phospho-Cdc25A (Ser76)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CDC25A

Gene Alias

CDC25 isoform A1-CAG; CDC25A; CDC25A2; CDC25A2-CAG isoform; Cdc25m3; cell division cycle 25A; D9Ertd393e; dual specificity phosphatase Cdc25A; EC 3.1.3.48; M-phase inducer phosphatase 1; MPIP1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12530, 171102, 993

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1.51 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.

P30304, P48964, P48965

Gene Symbols

CDC25A

Immunogen

A synthetic phosphorylated peptide around S76 of human CDC25A (NP_0017802)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Samples: NIH/3T3 Immunogen sequence: MGSSE CDC25a is a member of the CDC25 family of phosphatases
  • Three CDC25 genes are present in human cells: CDC25A, CDC25B, and CDC25C
  • These three genes function at different phases of the cell cycle
  • CDC25a is required for progression through G1 and S phases of the cell cycle
  • CDC25a activates the cyclin-dependent kinase CDC2 by removing two phosphate groups
  • CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division
  • CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated.