Phospho-STING (Ser365) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5117271-Each-of-1 | In Stock | ₹ 47,570.50 |
PIPA5117271 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,570.50
GST (18%): ₹ 8,562.69
Total Price: ₹ 56,133.19
Antigen
Phospho-STING (Ser365)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TMEM173
Gene Alias
2610307O08Rik; endoplasmic reticulum IFN stimulator; endoplasmic reticulum interferon stimulator; ERIS; hMITA; hSTING; hypothetical LOC533661; mediator of IRF3 activation; Mita; mitochondrial mediator of IRF3 activation; mitochondrial transmembrane protein 173; MMITA; Mpys; mSTING; NET23; N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner; poSTING; RGD1562552; rSTING; SAVI; Stimulator of interferon genes protein; stimulator of interferon response cGAMP interactor 1; STING; STING1; tm173; Tmem173; Transmembrane protein 173
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
340061, 72512
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.56 mg/mL
Formulation
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Accession No.
Q3TBT3, Q86WV6
Gene Symbols
TMEM173
Immunogen
A synthetic phosphorylated peptide around S365 of mouse STING (NP_0825371)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: THP-1 Immunogen sequence: LISGMD STING is a 379 amino acid containing signaling protein that acts as an important component of innate immune signaling
- This signaling protein is able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon (IFN-alpha and IFN-beta) and exert a potent anti-viral state following expression
- STING may have translocon function, the translocon possibly being able to influence the induction of type I interferons and is also involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II) thus facilitating the detection of intracellular viral RNA species as well as B-form DNA and mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway
- Generally seen in endoplasmic reticulum membrane, cell membrane and mitochondrion outer membrane, it is ubiquitously expressed in most of tissues.