PIPA5117808

BEND3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5117808-Each-of-1 In Stock ₹ 39,427.00

PIPA5117808 - Each of 1

₹ 39,427.00

In Stock

Quantity

1

Base Price: ₹ 39,427.00

GST (18%): ₹ 7,096.86

Total Price: ₹ 46,523.86

Antigen

BEND3

Classification

Polyclonal

Formulation

PBS with 0.03% ProClin 300; pH 7

Gene Accession No.

Q5T5X7

Gene Symbols

BEND3

Immunogen

E. coli-derived Human BEND3 fragment

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate

Unconjugated

Gene

BEND3

Gene Alias

BEN domain containing 3; BEN domain-containing protein 3; Bend3; KIAA1553; mKIAA1553

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

57673

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG

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Description

  • Transcriptional repressor which associates with the NoRC (nucleolar remodeling complex) complex and plays a key role in repressing rDNA transcription
  • The sumoylated form modulates the stability of the NoRC complex component BAZ2A/TIP5 by controlling its USP21-mediated deubiquitination (PubMed:21914818, PubMed:26100909)
  • Binds to unmethylated major satellite DNA and is involved in the recruitment of the Polycomb repressive complex 2 (PRC2) to major satellites
  • Stimulates the ERCC6L translocase and ATPase activities (PubMed:28977671)
  • [UniProt]