PIPA5118242

MINA53 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5118242-Each-of-1 In Stock ₹ 39,427.00

PIPA5118242 - Each of 1

₹ 39,427.00

In Stock

Quantity

1

Base Price: ₹ 39,427.00

GST (18%): ₹ 7,096.86

Total Price: ₹ 46,523.86

Antigen

MINA53

Classification

Polyclonal

Formulation

PBS with 0.03% ProClin 300; pH 7

Gene Accession No.

Q8IUF8

Gene Symbols

RIOX2

Immunogen

E. coli-derived Human MINA/MINA53/RIOX2 fragment

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Immunocytochemistry, Immunoprecipitation, Western Blot

Conjugate

Unconjugated

Gene

RIOX2

Gene Alias

1810047J07Rik; 2410057H13Rik; 3830408E23Rik; 60S ribosomal protein L27a histidine hydroxylase; AI449204; Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA; DKFZp762O1912; FLJ14393; histone lysine demethylase MINA; MDIG; mina; mina {ECO:0000312; Mina53; Mina-53; mineral dust induced gene protein; mineral dust-induced gene protein; MYC induced nuclear antigen; myc-induced nuclear antigen; myc-induced nuclear antigen, 53 kDa; NO52; Nucleolar protein 52; Protein mina53; RGD:708521}; Ribosomal oxygenase 2; Ribosomal oxygenase MINA; RIOX2; ROX

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

84864

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG

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Description

  • MINA is nuclear localized, myc-inducible protein that is thought to play a role in mammalian cell proliferation
  • Treatment of cancer cells lines such as the colon cancer cell line SW680 with siRNA against MINA inhibits cell growth, demonstrating that MINA may be a potential therapeutic target
  • MINA regulates several genes related to cell adhesion and metabolism that have also been shown to be regulated by c-Myc, but also regulates other genes whose expression are not modulated by c-Myc such as EGFR, IL-6 and HGF
  • MINA has also been found to act as a repressor to IL-4 expression in T cells, indicating that it may also play a role in T cell differentiation and genetic variation in T helper type 2 bias.