HLA-DRA Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5119196-Each-of-1 | In Stock | ₹ 42,408.50 |
PIPA5119196 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,408.50
GST (18%): ₹ 7,633.53
Total Price: ₹ 50,042.03
Antigen
HLA-DRA
Classification
Polyclonal
Conjugate
Unconjugated
Gene
HLA-DRA
Gene Alias
histocompatibility antigen HLA-DR alpha; HLA class II histocompatibility antigen, DR alpha chain; HLA-DRA; HLA-DRA1; major histocompatibility complex, class II, DR alpha; MHC cell surface glycoprotein; MHC class II antigen DRA; MLRW
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3122
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.
P01903
Gene Symbols
HLA-DRA
Immunogen
Recombinant protein HLA Class II Histocompatibility Antigen, DR Alpha Chain. The antigen corresponds to amino acid range 27-216 of the target protein.
Quantity
200 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- HLA-DRA is one of the HLA class II alpha chain paralogues
- This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane
- It plays a central role in the immune system by presenting peptides derived from extracellular proteins
- Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages)
- The alpha chain is approximately 33-35 kDa and its gene contains 5 exons
- Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail
- DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5
- HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.