PIPA5120245

CYP17A1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5120245-Each-of-1 In Stock ₹ 44,811.50

PIPA5120245 - Each of 1

₹ 44,811.50

In Stock

Quantity

1

Base Price: ₹ 44,811.50

GST (18%): ₹ 8,066.07

Total Price: ₹ 52,877.57

Antigen

CYP17A1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CYP17A1

Gene Alias

17a-hydroxylase; 17-alpha-hydroxyprogesterone aldolase; CPT7; Cyp17; Cyp17a1; CYPXVII; cytochrome P450 17A1; cytochrome P450 family 17 subfamily A member 1; cytochrome p450 XVIIA1; cytochrome P450, 17; cytochrome P450, 17a1; cytochrome P450, family 17, subfamily A, polypeptide 1; cytochrome P450, subfamily 17; Cytochrome P450, subfamily XVII; cytochrome P450, subfamily XVII (steroid 17-alpha-hydroxylase), adrenal hyperplasia; Cytochrome P450c17; cytochrome P450-C17; HGNC:2593; P45017alpha; p450c17; P450-C17; S17AH; steroid 17-alpha hydroxylase; steroid 17-alpha-hydroxylase/17,20 lyase; Steroid 17-alpha-monooxygenase

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

25146

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.45 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P11715

Gene Symbols

CYP17A1

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 209-508 of human CYP17A1 (NP_000093.1).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Positive test controls include: Rat testis
  • The target is usually found in the following locations: Membrane
  • Immunogen sequence: LSKDSLVDLV PWLKIFPNKT LEKLKSHVKI RNDLLNKILE NYKEKFRSDS ITNMLDTLMQ AKMNSDNGNA GPDQDSELLS DNHILTTIGD IFGAGVETTT SVVKWTLAFL LHNPQVKKKL YEEIDQNVGF SRTPTISDRN RLLLLEATIR EVLRLRPVAP MLIPHKANVD SSIGEFAVDK GTEVIINLWA LHHNEKEWHQ PDQFMPERFL NPAGTQLISP SVSYLPFGAG PRSCIGEILA RQELFLIMAW LLQRFDLEVP DDGQLPSLEG IPKVVFLIDS FKVKIKVRQA WREAQAEGST This gene encodes a member of the cytochrome P450 superfamily of enzymes
  • The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids
  • This protein localizes to the endoplasmic reticulum
  • It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens
  • Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia.