A2M Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5120391-Each-of-1 | In Stock | ₹ 44,811.50 |
PIPA5120391 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,811.50
GST (18%): ₹ 8,066.07
Total Price: ₹ 52,877.57
Antigen
A2M
Classification
Polyclonal
Conjugate
Unconjugated
Gene
A2M
Gene Alias
A2M; A2m1; A2maa; A2MAC1; A2MD; A2mp; Alpha 2 M; Alpha-2-M; Alpha-2-M (A2M); alpha-2-macroglobulin; Alpha-2-macroglobulin-P; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5; CPAMD5; DKFZp779B086; FWP007; LOC100061656; Mam; S863 7; S863-7
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
2, 232345, 24153
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
2.44 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.
P01023, P06238, Q6GQT1
Gene Symbols
A2M
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1155-1474 of human Alpha-2-Macroglobulin (Alpha-2-Macroglobulin (A2M)) (NP_0000052)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive test controls include: SH-SY5Y, Mouse kidney, Mouse ovary, Rat spinal cord
- The target is usually found in the following locations: Secreted
- Immunogen sequence: ALAGNQDKRK EVLKSLNEEA VKKDNSVHWE RPQKPKAPVG HFYEPQAPSA EVEMTSYVLL AYLTAQPAPT SEDLTSATNI VKWITKQQNA QGGFSSTQDT VVALHALSKY GAATFTRTGK AAQVTIQSSG TFSSKFQVDN NNRLLLQQVS LPELPGEYSM KVTGEGCVYL QTSLKYNILP EKEEFPFALG VQTLPQTCDE PKAHTSFQIS LSVSYTGSRS ASNMAIVDVK MVSGFIPLKP TVKMLERSNH VSRTEVSSNH VLIYLDKVSN QTLSLFFTVL QDVPVRDLKP AIVKVYDYYE TDEFAIAEYN APCSKDLGNA Alpha 2-Macroglobulin (a2M), is a approximately 720-kDa homotetrameric glycoprotein composed of four identical approximately 180 kDa subunits
- aAlpha 2M shares with other alpha-macroglobulins, like the complement components C3 and C4 and the pregnancy zone protein PZP, an extraordinary binding capacity for a variety of ligands
- This allows the alpha-macroglobulins to serve as humoral defense barriers against foreign peptides in the plasma
- Alpha 2M interacts and captures virtually any proteinase, often referred to as a panprotease inhibitor
- In the brain of Alzheimer's disease (AD) patients, Alpha 2M also has been localized to diffuse amyloid plaques, supporting an important role for alpha 2M in AD etiopathology.