CTNNA3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5120461-Each-of-1 | In Stock | ₹ 44,811.50 |
PIPA5120461 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,811.50
GST (18%): ₹ 8,066.07
Total Price: ₹ 52,877.57
Antigen
CTNNA3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CTNNA3
Gene Alias
4930429L08Rik; 4933408A16; Alpha T-catenin; Alpha-3 catenin; alpha-catenin-like protein; alpha-T-catenin; ARVD13; Cadherin-associated protein; catenin (cadherin associated protein), alpha 3; catenin (cadherin-associated protein), alpha 3; catenin alpha 3; catenin alpha-3; Catna3; CTNNA3; RGD1559455; RGD1562230; Vr22
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
216033, 29119, 361839
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1.58 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.
Q65CL1, Q9UI47
Gene Symbols
CTNNA3
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human CTNNA3 (NP_001278062.1).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive test controls include: LO2, 293T, Mouse spleen, Rat brain
- The target is usually found in the following locations: Cytoplasm, cytoskeleton
- Immunogen sequence: MKSTQRREKQ GSMSAETPIT LNIDPQDLQV QTFTVEKLLE PLIIQVTTLV NCPQNPSSRK KGRSKRASVL LASVEEATWN LLDKGEKIAQ EATVLKDELT ASLEEVRKES EALKVSAERF TDDPCFLPKR EAVVQAARAL LAAVTRLLIL ADMIDVMCLL QHVSAFQRTF ESLKNVANKS DLQKTYQKLG KELENLDYLA FKRQQDLKSP NQRDEIAGAR ASLKENSPLL HSICSACLEH Catenins are proteins that connect cadherin/beta-catenin cell adhesion complexes to the actin cytoskeleton
- Although originally discovered in testis, alphaT-catenin is expressed in other tissues, the highest levels being observed in heart
- Immunohistochemical analysis showed human alphaTcatenin localization at intercalated discs of cardiomyocytes and in peritubular myoid cells of testis
- It is proven that alphaT-catenin can functionally restore cell-cell adhesion in colon cancer cells lacking alpha-catenins
- This indicates that this protein is involved in the formation of specific cell-cell contacts in specific types of muscle cells
- The encoded protein has about the same predicted size (100 kDa) as other alpha-catenins to which it shows an overall amino acid identity of 57%
- In cells transfected with alphaT-catenin cDNA, interaction with alpha-catenin was demonstrated by coimmunoprecipitation
- The 892_24D2S antibody against alphaT-catenin does not show any cross reaction with alphaE-catenin or alphaNcatenin in western blot analysis.