LDB3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5121105-Each-of-1 | In Stock | ₹ 44,811.50 |
PIPA5121105 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,811.50
GST (18%): ₹ 8,066.07
Total Price: ₹ 52,877.57
Antigen
LDB3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
LDB3
Gene Alias
AW742271; cardiomyopathy, dilated 1C (autosomal dominant); CMD1C; CMH24; CMPD3; cypher; FLJ35865; HGNC:15710; KIAA01613; KIAA0613; LDB3; LDB3Z1; LDB3Z4; LIM domain binding 3; LIM domain-binding protein 3; LVNC3; MFM4; ORACLE; oracle protein; PDLIM6; PDZ and LIM domain 6; PDZ-LIM domain protein; protein cypher; Protein oracle; RGD1564875; ZASP; Z-band alternatively spliced PDZ motif protein; Z-band alternatively spliced PDZ-motif protein
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
11155, 24131, 498587
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1.12 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
O75112, Q9JKS4
Gene Symbols
LDB3
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-283 of human LDB3 (NP_001073585.1).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive test controls include: HL-60, MCF7, U-937, Raji, BT-474, Mouse skeletal muscle, Rat skeletal muscle
- The target is usually found in the following locations: Cell projection, Cytoplasm, Z line, cytoskeleton, myofibril, perinuclear region, pseudopodium, sarcomere
- Immunogen sequence: MSYSVTLTGP GPWGFRLQGG KDFNMPLTIS RITPGSKAAQ SQLSQGDLVV AIDGVNTDTM THLEAQNKIK SASYNLSLTL QKSKRPIPIS TTAPPVQTPL PVIPHQKVVV NSPANADYQE RFNPSALKDS ALSTHKPIEV KGLGGKATII HAQYNTPISM YSQDAIMDAI AGQAQAQGSD FSGSLPIKDL AVDSASPVYQ AVIKSQNKPE DEADEWARRS SNLQSRSFRI LAQMTGTEFM QDPDEEALRR SRERFETERN SPRFAKLRNW HHGLSAQILN VKS This gene encodes a PDZ domain-containing protein
- PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues
- PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins
- The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains
- The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules
- This protein also interacts with all three members of the myozenin family
- Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy
- Alternatively spliced transcript variants encoding different isoforms have been identified; all isoforms have N-terminal PDZ domains while only longer isoforms (1, 2 and 5) have C-terminal LIM domains.