PIPA5121992

Fumarase Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5121992-Each-of-1 In Stock ₹ 17,346.10

PIPA5121992 - Each of 1

₹ 17,346.10

In Stock

Quantity

1

Base Price: ₹ 17,346.10

GST (18%): ₹ 3,122.298

Total Price: ₹ 20,468.398

Antigen

Fumarase

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Fh1

Gene Alias

EF-3; Fh; Fh1; Fh-1; FMRD; fumarase; fumarate hydratase; fumarate hydratase 1; fumarate hydratase, mitochondrial; HLRCC; LRCC; MCL; MCUL1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14193, 14194

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

500 μg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.

P97807

Gene Symbols

FH, Fh1

Immunogen

Recombinant protein Fumarase. The antigen corresponds to amino acid range 42-185 of the target protein.

Quantity

20 μL

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • The protein encoded by this gene is an enzymatic component of the tricarboxylic acid cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate
  • It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used
  • The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm
  • It is similar to some thermostable class II fumarases and functions as a homotetramer
  • Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.