DATF1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5122041-Each-of-1 | In Stock | ₹ 17,346.10 |
PIPA5122041 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 17,346.10
GST (18%): ₹ 3,122.298
Total Price: ₹ 20,468.398
Antigen
DATF1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
DIDO1
Gene Alias
6720461J16Rik; BYE1; C20orf158; D130048F08Rik; DATF1; DATF-1; death associated transcription factor 1; death inducer-obliterator 1; death inducer-obliterator-2; death inducer-obliterator-3; death-associated transcription factor 1; Death-inducer obliterator 1; dido; Dido1; DIDO2; DIDO3; DIO1; DIO-1; dJ885L7.8; KIAA0333
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
11083
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
500 μg/mL
Formulation
PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.
Q9BTC0
Gene Symbols
DIDO1
Immunogen
Recombinant protein Death Inducer Obliterator 1. The antigen corresponds to amino acid range 258-455 of the target protein.
Quantity
20 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Dio-1 (Death Inducer-Obliterator-1) is a putative transcription factor that contains two zinc finger motifs
- Dio-1 translocates to the nucleus, and activates apoptosis during limb development
- Programmed cell death, a highly regulated form of apoptosis, plays an important role in determining the amount of tissue, the shape, and the definition of each digit during limb development
- Dio-1 expression is upregulated when an apoptotic signal is detected, and subsequently apoptosis is induced
- This process is similar to the expression of NFkB and NGF in response to external signals
- Dio-1 expression is suppressed by caspase inhibitors and Bcl-2 expression
- This supports the theory that Dio-1 functions in the onset of programmed cell death.