Phospho-CDK7 (Thr170) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA512573-Each-of-1 | In Stock | ₹ 49,261.50 |
PIPA512573 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,261.50
GST (18%): ₹ 8,867.07
Total Price: ₹ 58,128.57
Antigen
Phospho-CDK7 (Thr170)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CDK7
Gene Alias
39 KDa protein kinase; 39 protein kinase; AI323415; AI528512; C230069N13; CAK; CAK1; CDK; CDK7; CDK-activating kinase; CDK-activating kinase 1; Cdkn7; cell division protein kinase 7; CR4 protein kinase; CRK4; CRK4 PK (CDC2-related-kinase-4 protein kinase); cyclin dependent kinase 7; cyclin-dependent kinase 7; cyclin-dependent kinase 7 (homolog of Xenopus MO15 cdk-activating kinase); cyclin-dependent kinase 7 (MO15 homolog Xenopus laevis cdk-activating kinase); cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase); EC 2.7.11.22; EC 2.7.11.23; HCAK; homolog of Xenopus MO15 Cdk-activating kinase; kinase subunit of CAK; MO15; Mpk-7; OTTHUMP00000222032; OTTHUMP00000222033; p39 Mo15; p39MO15; Protein-tyrosine kinase MPK-7; serine/threonine kinase stk1; serine/threonine protein kinase 1; serine/threonine protein kinase MO15; Serine/threonine-protein kinase 1; STK1; TFIIH basal transcription factor complex kinase subunit
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1022
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Dot Blot, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
P50613
Gene Symbols
CDK7
Immunogen
KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T170 of human CDK7
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This antibody is predicted to react with mouse based on sequence homology
- The trimeric complex of CDK7, cyclin H and MNAT1, functions as a Cdk-activating kinase (CAK)
- It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair
- This complex is thought to serve as a direct link between the regulation of transcription and the cell cycle
- The bound complex is important in the normal double-strand break repair function of breast cancer, type 1 (BRCA1)
- CDK7 may be a target of germline cancer-inducing mutations.