PIPA5142036
DPF1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5142036-Each-of-1 | In Stock | ₹ 40,317.00 |
PIPA5142036 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,317.00
GST (18%): ₹ 7,257.06
Total Price: ₹ 47,574.06
Antigen
DPF1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
DPF1
Gene Alias
Baf45b; BRG1-associated factor 45B; D4, zinc and double PHD fingers family 1; double PHD fingers 1; DPF1; NEU BAF45b; NEUD4; neuro-d4; neuro-d4 homolog; neuronal d4 domain family member; zinc finger protein neuro-d4
Host Species
Goat
Purification Method
Ammonium sulfate precipitation
Regulatory Status
RUO
Gene ID (Entrez)
8193
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Isotype
IgG
Applications
Immunocytochemistry, Western Blot
Concentration
0.5 mg/mL
Formulation
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q92782
Gene Symbols
DPF1
Immunogen
Peptide with sequence C-HLKEKASAYITLT.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Related Products
Description
- Additional Information: This antibody is expected to recognize all three reported isoforms (NP_001128627.1; NP_004638.2; NP_001128628.1)
- This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:2,000
- May have an important role in developing neurons by participating in regulation of cell survival, possibly as a neurospecific transcription factor
- Belongs to the neuron-specific chromatin remodeling complex (nBAF complex)
- During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state
- The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes
- As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF)
- The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells
- The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth.