PAPD5 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5142750-Each-of-1 | In Stock | ₹ 40,317.00 |
PIPA5142750 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,317.00
GST (18%): ₹ 7,257.06
Total Price: ₹ 47,574.06
Antigen
PAPD5
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PAPD5
Gene Alias
5730445M16Rik; 5830428A09; GLD4; Non-canonical poly(A) RNA polymerase PAPD5; PAP associated domain containing 5; PAP-associated domain-containing protein 5; PAPD5; poly(A) RNA polymerase D5, non-canonical; Tent4b; Terminal guanylyltransferase; Terminal nucleotidyltransferase 4B; terminal uridylyltransferase 3; Topoisomerase-related function protein 4-2; TRF4-2; TUT3; TUTase 3
Host Species
Goat
Purification Method
Ammonium sulfate precipitation
Regulatory Status
RUO
Gene ID (Entrez)
214627, 307745
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Isotype
IgG
Applications
Western Blot
Concentration
0.5 mg/mL
Formulation
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q68ED3
Gene Symbols
PAPD5
Immunogen
Peptide with sequence C-TDEVATYRDWISKQ.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse, Rat
Form
Liquid
Related Products
Description
- Additional Information: This antibody is expected to recognize both reported isoforms (NP_001035374.2; NP_001035375.2)
- This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000
- Terminal nucleotidyltransferase that catalyzes preferentially the transfert of ATP and GTP on RNA 3' poly(A) tail creating a heterogeneous 3' poly(A) tail leading to mRNAs stabilization by protecting mRNAs from active deadenylation (PubMed:21788334, PubMed:30026317)
- Also functions as a catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism
- Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates
- Doesn't need a cofactor for polyadenylation activity (in vitro) (PubMed:21788334, PubMed:21855801)
- Required for cytoplasmic polyadenylation of mRNAs involved in carbohydrate metabolism, including the glucose transporter SLC2A1/GLUT1 (PubMed:28383716)
- Plays a role in replication-dependent histone mRNA degradation, probably through terminal uridylation of mature histone mRNAs
- May play a role in sister chromatid cohesion (PubMed:18172165)
- Mediates 3' adenylation of the microRNA MIR21 followed by its 3'-to-5' trimming by the exoribonuclease PARN leading to degradation (PubMed:25049417)
- Mediates 3' adenylation of H/ACA box snoRNAs (small nucleolar RNAs) followed by its 3'-to-5' trimming by the exoribonuclease PARN which enhances snoRNA stability and maturation (PubMed:22442037)
- [UniProt]